There are
1,355 mi
from Appleton, WI to Seminole, FL
That's the driving distance. It would take 1 day 1 hour to go from Appleton, Wisconsin to Seminole, Florida.
The flight distance (direct flight from Appleton, WI to Seminole, FL) is 1,176.60 mi.
1,355 mi = 1.61 kms