There are
939 mi
from Appleton, WI to Scottsbluff, NE
That's the driving distance. It would take 17 hours 22 mins to go from Appleton, Wisconsin to Scottsbluff, Nebraska.
The flight distance (direct flight from Appleton, WI to Scottsbluff, NE) is 785.92 mi.
939 mi = 1,511.06 kms