There are
379 mi
from Appleton, WI to Ottumwa, IA
That's the driving distance. It would take 7 hours 44 mins to go from Appleton, Wisconsin to Ottumwa, Iowa.
The flight distance (direct flight from Appleton, WI to Ottumwa, IA) is 302.39 mi.
379 mi = 609.65 kms