Miles between Appleton, WI and Kirksville, MO

There are
443 mi
from Appleton, WI to Kirksville, MO

That's the driving distance. It would take 9 hours 3 mins to go from Appleton, Wisconsin to Kirksville, Missouri.

The flight distance (direct flight from Appleton, WI to Kirksville, MO) is 352.65 mi.

443 mi = 712.33 kms