There are
560 mi
from Appleton, WI to Hopkinsville, KY
That's the driving distance. It would take 11 hours 33 mins to go from Appleton, Wisconsin to Hopkinsville, Kentucky.
The flight distance (direct flight from Appleton, WI to Hopkinsville, KY) is 513.33 mi.
560 mi = 900.96 kms