There are
1,560 mi
from Appleton, WI to Harlingen, TX
That's the driving distance. It would take 1 day 4 hours to go from Appleton, Wisconsin to Harlingen, Texas.
The flight distance (direct flight from Appleton, WI to Harlingen, TX) is 1,351.85 mi.
1,560 mi = 1.61 kms