There are
2,054 mi
from Antioch, CA to Festus, MO
That's the driving distance. It would take 1 day 11 hours to go from Antioch, California to Festus, Missouri.
The flight distance (direct flight from Antioch, CA to Festus, MO) is 1,699.30 mi.
2,054 mi = 3.22 kms