Miles between Ann Arbor, MI and Lancaster, SC

There are
648 mi
from Ann Arbor, MI to Lancaster, SC

That's the driving distance. It would take 12 hours 52 mins to go from Ann Arbor, Michigan to Lancaster, South Carolina.

The flight distance (direct flight from Ann Arbor, MI to Lancaster, SC) is 546.43 mi.

648 mi = 1,042.74 kms