Miles between Ann Arbor, MI and Lancaster, SC

There are
649 mi
from Ann Arbor, MI to Lancaster, SC

That's the driving distance. It would take 13 hours 3 mins to go from Ann Arbor, Michigan to Lancaster, South Carolina.

The flight distance (direct flight from Ann Arbor, MI to Lancaster, SC) is 546.43 mi.

649 mi = 1,043.91 kms