Miles between Ann Arbor, MI and Greenville, SC

There are
645 mi
from Ann Arbor, MI to Greenville, SC

That's the driving distance. It would take 12 hours 40 mins to go from Ann Arbor, Michigan to Greenville, South Carolina.

The flight distance (direct flight from Ann Arbor, MI to Greenville, SC) is 518.37 mi.

645 mi = 1,038.41 kms