There are
3,907 mi
from Anchorage, AK to Sikeston, MO
That's the driving distance. It would take 3 days 5 hours to go from Anchorage, Alaska to Sikeston, Missouri.
The flight distance (direct flight from Anchorage, AK to Sikeston, MO) is 3,055.05 mi.
3,907 mi = 4.83 kms