There are
4,349 mi
from Anchorage, AK to Lexington, SC
That's the driving distance. It would take 3 days 15 hours to go from Anchorage, Alaska to Lexington, South Carolina.
The flight distance (direct flight from Anchorage, AK to Lexington, SC) is 3,494.04 mi.
4,349 mi = 6.44 kms