There are
3,770 mi
from Anchorage, AK to Clayton, MO
That's the driving distance. It would take 3 days 3 hours to go from Anchorage, Alaska to Clayton, Missouri.
The flight distance (direct flight from Anchorage, AK to Clayton, MO) is 2,933.71 mi.
3,770 mi = 4.83 kms