There are
1,208 mi
from Amarillo, TX to Waynesville, NC
That's the driving distance. It would take 21 hours 23 mins to go from Amarillo, Texas to Waynesville, North Carolina.
The flight distance (direct flight from Amarillo, TX to Waynesville, NC) is 1,060.33 mi.
1,208 mi = 1.61 kms