There are
1,293 mi
from Amarillo, TX to South Lake Tahoe, CA
That's the driving distance. It would take 23 hours 45 mins to go from Amarillo, Texas to South Lake Tahoe, California.
The flight distance (direct flight from Amarillo, TX to South Lake Tahoe, CA) is 1,031.05 mi.
1,293 mi = 2,080.12 kms