There are
1,539 mi
from Amarillo, TX to Shasta Lake, CA
That's the driving distance. It would take 1 day 3 hours to go from Amarillo, Texas to Shasta Lake, California.
The flight distance (direct flight from Amarillo, TX to Shasta Lake, CA) is 1,177.61 mi.
1,539 mi = 2,477.31 kms