There are
1,358 mi
from Amarillo, TX to San Mateo, CA
That's the driving distance. It would take 23 hours 55 mins to go from Amarillo, Texas to San Mateo, California.
The flight distance (direct flight from Amarillo, TX to San Mateo, CA) is 1,148.97 mi.
1,358 mi = 2,185.02 kms