There are
960 mi
from Amarillo, TX to Owensboro, KY
That's the driving distance. It would take 17 hours 9 mins to go from Amarillo, Texas to Owensboro, Kentucky.
The flight distance (direct flight from Amarillo, TX to Owensboro, KY) is 835.40 mi.
960 mi = 1,544.68 kms