There are
528 mi
from Amarillo, TX to Nacogdoches, TX
That's the driving distance. It would take 9 hours 48 mins to go from Amarillo, Texas to Nacogdoches, Texas.
The flight distance (direct flight from Amarillo, TX to Nacogdoches, TX) is 483.29 mi.
528 mi = 849.73 kms