There are
1,461 mi
from Amarillo, TX to Myrtle Beach, SC
That's the driving distance. It would take 1 day 2 hours to go from Amarillo, Texas to Myrtle Beach, South Carolina.
The flight distance (direct flight from Amarillo, TX to Myrtle Beach, SC) is 1,308.56 mi.
1,461 mi = 1.61 kms