There are
852 mi
from Amarillo, TX to Mesquite, NV
That's the driving distance. It would take 16 hours 1 min to go from Amarillo, Texas to Mesquite, Nevada.
The flight distance (direct flight from Amarillo, TX to Mesquite, NV) is 692.04 mi.
852 mi = 1,371.51 kms