There are
1,220 mi
from Amarillo, TX to Lompoc, CA
That's the driving distance. It would take 21 hours 38 mins to go from Amarillo, Texas to Lompoc, California.
The flight distance (direct flight from Amarillo, TX to Lompoc, CA) is 1,054.37 mi.
1,220 mi = 1.61 kms