There are
1,393 mi
from Amarillo, TX to Hanahan, SC
That's the driving distance. It would take 1 day 1 hour to go from Amarillo, Texas to Hanahan, South Carolina.
The flight distance (direct flight from Amarillo, TX to Hanahan, SC) is 1,256.30 mi.
1,393 mi = 1.61 kms