There are
1,080 mi
from Amarillo, TX to El Cajon, CA
That's the driving distance. It would take 18 hours 49 mins to go from Amarillo, Texas to El Cajon, California.
The flight distance (direct flight from Amarillo, TX to El Cajon, CA) is 881.84 mi.
1,080 mi = 1.61 kms