There are
1,241 mi
from Amarillo, TX to Easley, SC
That's the driving distance. It would take 22 hours 4 mins to go from Amarillo, Texas to Easley, South Carolina.
The flight distance (direct flight from Amarillo, TX to Easley, SC) is 1,086.64 mi.
1,241 mi = 1.61 kms