There are
447 mi
from Tulsa, OK to Cape Girardeau, MO
That's the driving distance. It would take 8 hours 24 mins to go from Tulsa, Oklahoma to Cape Girardeau, Missouri.
The flight distance (direct flight from Tulsa, OK to Cape Girardeau, MO) is 367.18 mi.
447 mi = 719.50 kms