There are
1,441 mi
from Tucson, AZ to Edwardsville, IL
That's the driving distance. It would take 1 day 2 hours to go from Tucson, Arizona to Edwardsville, Illinois.
The flight distance (direct flight from Tucson, AZ to Edwardsville, IL) is 1,260.67 mi.
1,441 mi = 1.61 kms