There are
2,647 mi
from San Francisco, CA to Spartanburg, SC

That's the driving distance. It would take 1 day 23 hours to go from San Francisco, California to Spartanburg, South Carolina.

The flight distance (direct flight from San Francisco, CA to Spartanburg, SC) is 2,243.61 mi.

2,647 mi = 3.22 kms