There are
2,816 mi
from San Francisco, CA to Mebane, NC
That's the driving distance. It would take 2 days 1 hour to go from San Francisco, California to Mebane, North Carolina.
The flight distance (direct flight from San Francisco, CA to Mebane, NC) is 2,364.74 mi.
2,816 mi = 3.22 kms