There are
1,684 mi
from San Diego, CA to Maryville, MO
That's the driving distance. It would take 1 day 5 hours to go from San Diego, California to Maryville, Missouri.
The flight distance (direct flight from San Diego, CA to Maryville, MO) is 1,340.07 mi.
1,684 mi = 1.61 kms