There are
1,561 mi
from Mesa, AZ to Muscle Shoals, AL
That's the driving distance. It would take 1 day 4 hours to go from Mesa, Arizona to Muscle Shoals, Alabama.
The flight distance (direct flight from Mesa, AZ to Muscle Shoals, AL) is 1,382.53 mi.
1,561 mi = 1.61 kms