There are
1,087 mi
from Louisville, KY to Key Biscayne, FL

That's the driving distance. It would take 19 hours 58 mins to go from Louisville, Kentucky to Key Biscayne, Florida.

The flight distance (direct flight from Louisville, KY to Key Biscayne, FL) is 927.14 mi.

1,087 mi = 1.61 kms