There are
1,635 mi
from Las Vegas, NV to Sikeston, MO

That's the driving distance. It would take 1 day 4 hours to go from Las Vegas, Nevada to Sikeston, Missouri.

The flight distance (direct flight from Las Vegas, NV to Sikeston, MO) is 1,419.78 mi.

1,635 mi = 1.61 kms