There are
1,511 mi
from Las Vegas, NV to Kirksville, MO
That's the driving distance. It would take 1 day 2 hours to go from Las Vegas, Nevada to Kirksville, Missouri.
The flight distance (direct flight from Las Vegas, NV to Kirksville, MO) is 1,255.74 mi.
1,511 mi = 1.61 kms