There are
1,702 mi
from Las Vegas, NV to Cape Girardeau, MO
That's the driving distance. It would take 1 day 5 hours to go from Las Vegas, Nevada to Cape Girardeau, Missouri.
The flight distance (direct flight from Las Vegas, NV to Cape Girardeau, MO) is 1,420.78 mi.
1,702 mi = 1.61 kms